Space medicine deals with the field of research involved with the adaptation of humans to the unique environment of space. It supports survival, function in this challenging and lethal environment. The day will come when some human beings will spend all their time in space. It is international, intercultural and interdisciplinary, operating at the boundaries of exploration, science and medicine. Motion sickness, negative nitrogen and calcium balance, anemia and radiation exposure, are medical problems seen in space, issues that already affect medical practice outside aerospace medicine. Space medicine doctors have a great responsibility to space workers and spaceflight participants. Flight surgeons help in developing mitigation strategies to ensure the safety, health and performance of space travelers and which is an extreme and hazardous environment. This includes all phases from selection, training and spaceflight itself to post-flight rehabilitation and long-term health.

The purpose of this paper is to draw attention towards the emerging fields of nanotechnology. Nanomedicine is a therapeutic process which will turn out to be a phenomenal drug delivery system. Nanorobots is an advanced technology and currently, the research is in progress to use nanorobots in diagnosis, treating and preventing the disease. This is for improving the human health. The main purpose of nanorobots is to cure many dreadful diseases in human body. Nanorobotics includes the study of design and construction of robots. The technology works at an atomic, molecular or cellular level. Nanorobots are the tiny structures ranging about 1-100nm. The content of this paper will focus on the recent advances in nanorobotics and how the technology will be utilized in the medical application.

In this work we report the synthesis of nanoparticles (NPs) of solid crystalline materials with theranostic properties, based on the biocompatible components fructose and SrCl2 or SrI2. We suitably modified the NPs surface, with simple and fast methods, in order to allow their survival in biological environments. Preliminary viability assay and cell uptake tests were performed on non-tumor and tumor cell lines, hTERT-HME1 and HT-29, respectively. Furthermore, a simple computational tool to evaluate the specific activity of NPs containing 89Sr and 131I required to deliver a pre-determined dose to the cancer tissue was developed, in order to rapidly estimate the amount of NPs to be administered to the patient. The results are discussed in the context of developing novel biocompatible materials for personalized radionuclide therapy.

Plan: In Vivo Brain-Distribution Studies of Curcumin loaded Nanoemulsion for Nose to Brain Delivery. Preface: The aim of present investigation is to develop in vivo Brain-Distribution analysis for nose to brain targeting of curcumin loaded nanoemulsion (CRM-NE) via olfactory and trigeminal nerve pathways. Methodology: For nose to brain drug delivery analysis in terms of DTP (Direct Nose to Brain Transport Percentage) and DTE (Drug Targeting Efficiency). Outcome: These findings are in consequence with related reports by that nanoemulsions increase nose-to-brain uptake of drugs.

Liquisolid Technique is a novel technique. It is used to improve the dissolution rate of the poorly water soluble drugs like Loperamide. The liquisolid compacts were prepared by using carrier, coating material and liquid medication. Liquisolid compacts refer to the formulations that are formed by conversion of liquid drugs, drug suspension or solution in non-volatile solvents into dry non-adherent, free flowing and compressible powder mixture. Hence, the liquisolid technology allows the conversion of liquid systems into solid drug delivery systems such as Tablets. The crystallinity of the newly formulated drug and the interaction between excipients were examined by X - ray Powder Diffraction (X - RD) and Fourier-Transform Infrared Spectroscopy (FTIR). Finally among various formulations of Loperamide liquisolid compacts, the optimal formulation of the batch F2, prepared with 2% Propylene glycol and 20mg Aerosil showed an increased dissolution rate of poorly water soluble Loperamide drug of about 85% drug release within 15 minutes. Loperamide, is a Piperidine derivative and it is used as an Anti- diarrheal agent.