Fast-dissolving oral films have emerged as alternative dosage forms for the patients who experience difficulties in swallowing traditional oral solid dosage forms such as children and the elderly, but also to the general population. These are solid dosage forms, which disintegrate and dissolve immediately within 1 min when placed in the mouth without drinking water or mastication. This technology has been used for local action as well as rapid release products, to enhance drug bioavailability and also to mask the bitter taste of the drug. These formulations are suitable for cough, cold, sore throat, allergenic conditions, nausea, pain, hypertension and CNS disorders, epilepsy and many more diseases. This review reflects information regarding formulation consideration, manufacturing methods and evaluation tests employed in the preparation of fast dissolving oral films.

Conventional indefinite quantity forms that need multidose medical aid have several issues and complications. Today regarding seventy four of medicine are taken orally and are found to not be as effective as desired. To improve such characters percutaneous drug delivery system was emerged. Drug delivery through the skin to attain a general result of a drug is usually referred to as percutaneous drug delivery and differs from ancient topical drug delivery. Transdermal drug delivery systems (TDDS) are indefinite quantity forms involves drug transport to viable stratum and or dermal tissues of the skin for native therapeutic result whereas an awfully major fraction of drug is transported into the general blood circulation. The adhesive of the percutaneous drug delivery system is essential to the security, efficaciousness and quality of the merchandise. Topical administration of therapeutic agents offers several benefits over standard oral and invasive ways of drug delivery. Several vital benefits of percutaneous drug delivery limitation of viscous initial pass metabolism, sweetening of therapeutic potency and maintenance of steady plasma level of the drug. This article provides an outline of sorts of percutaneous patches, ways of preparation and its chemistry ways of analysis.

Scleropyrum pentandrum (Dennst) Mabb is found in the evergreen divine forests of northern Kerala belonging to santalaceae family. It is distributed in various other region of the world. It is used for it’s Anti inflammatory activity along with many other diseases by traditional house remedy. Various tribal people in different parts of the world it is using this plant. In this study, the aim was to investigate the anatomical characteristics of bark and roots of this medicinally important plant species. Much works on this medicinal plant is not reported till. Systematic and scientific further study is required to explore the complete identity of this plant.

Scleropyrum pentandrum [Dennst] Mabb is a small tree which is commonly found in the Western Ghats of India and evergreen sacred grooves of Northern Kerala. It is also known as hard pear, grows in the sandy soil of divine forests of coastal Kerala, Peninsular India, Western Ghats, South and Central Sahyadris. Scleropyrum pentandrum is used for its biological activities by the tribal community of different regions of world. This study explains the anti-bacterial activity of fruits of Scleropyrum pentandrum. The methanolic extract of fruits was tested for the anti-bacterial activity. Literature review of this plant proved the necessity of scientific evaluation, as very less work has been done with Scleropyrum pentandrum. Further study is needed to isolate and elucidate its medicinally active components. Also necessary studies are needed to evaluate each compound for its pharmacological activities.

Helminthiasis has been reported as the major cause of under nourishment, anaemia and other related ailment associated with children of developing countries. Development of patient friendly dosage forms has always been a challenge for formulation scientists. In this study an attempt to formulate a candy based lollipop of the drug Albendazole has been tried out for treatment of helminthiasis. Heating congealing method of preparation with three hydrocolloids namely Sodium carboxy methyl cellulose, Methyl cellulose and HPMC was attempted for lollipop formulation. The formulated lollipops were evaluated for drug content, weight variation, hardness, in vitro drug release and stability. The results revealed that F1 formulation with methyl cellulose 0.5% w/w polymer showed optimum characteristics, stability and a better drug release compared to other formulations.