The aim of this study was to evaluate the quality of ciprofloxacin hydrochloride tablets (500mg) of four brands which are available in Mangalore. Ciprofloxacin, a fluoroquinolone antimicrobial agent active against a broad spectrum of gramnegative and gram-positive organisms, including Pseudomonas aeruginosa and methicillin-resistant staphylococcus aureus. Quality test is a way to guarantee quality of drug products as many pharmaceutics can produce substandard drug products. In this project, ciprofloxacin hydrochloride of 500mg tablets were randomly selectedfrom three manufactures of Bangladesh and has been assessed according to the United States Pharmacopoeia and British Pharmacopoeia. Those products were subjected to seven key testssuch as-weight variation, hardness, dissolution test, drug content, disintegration test, friability and antimicrobial test. Assay of Ciprofloxacin Hydrochloride tablets showed that the samples of four brands had potency with in limit. In-vitro release study showed that the amount of ciprofloxacin released in 30 minutes was not less than 80% of the labeled amount which is in accordance with the pharmacopeias requirements. Results of all tests are satisfactorily well, which shows a high-quality performance. This study will provide a basis for further In-vivo studies. The tested oral ciprofloxacin products distributed in our country were proven that those products had good quality.

Ageratum conyzoides, family Asteraceae is a straight, grassy, annual, 30 to 80cm long, stems are covered with fine white hairs, leaves are opposite, puberty with long petioles and trichomes of glands which were used for in vitro assessment of the anti-inflammatory activity. Medically it is used for the treatment of burn, colic, collyrium, dyspepsia, emetic, eye problems, lithontriptic as purgative, sleep-sickness, sore throat, syphilis, uterine disorders, wound, etc. This study used the in-vitro HRBC method to identify the anti-inflammatory property of the aqueous, alcoholic, and hydroalcoholic extracts of the leaves and analyzed them. The result of this study revealed that alcoholic extracts (200mg/ml) of Ageratum conyzoides showed significant anti-inflammatory activity. This anti-inflammatory activity of Ageratum conyzoides was compared with the potency of a standard drug (diclofenac sodium).