This review delves into the intricate relationship between antioxidants and anti-inflammatory properties within edible oils, exploring their combined impact on human health. We analyze the synergistic effects of various compounds, shedding light on the mechanisms underlying enhanced health benefits. Explore specific antioxidants present in various edible oils, such as polyphenols, tocopherols and carotenoids. Highlight the diverse sources of these antioxidants, ranging from olive oil to sunflower oil. The molecular mechanisms by which antioxidants neutralize free radicals, emphasizing their role in preventing oxidative stress. The potential role of antioxidants rich edible oils in mitigating chronic diseases associated with inflammations. The influence of dietary patterns on the effectiveness of edible oils in providing antioxidant and anti-inflammatory benefits.

The purpose of the present study was to formulate and evaluate Gentamicin Sulfate niosomal gel. Gentamicin Sulfate is an aminoglycoside antibiotic used to prevent or treat wide variety of bacterial infections. Also used to treat minor skin infections (such as impetigo, folliculitis) eczema, psoriasis, minor burns/cuts/wounds. Topically applied niosomes can increase the residence time of drugs in the stratum corneum and epidermis while reducing the systemic absorption of the drug. The niosomal dispersion was evaluated for surface morphology, drug content, entrapment efficiency and in-vitro drug release. Among the six formulations of niosomes, F6 formulation showed 75.86% entrapment efficiency and the F4 formulation the drug content was found to be 79.39% and in-vitro drug release was found to be 87.01% at the end of 8 hrs. F4 was selected as the best formulation and this formulation was incorporated niosomal gel and evaluation for niosomal gel was determined by physical appearance, pH, viscosity, spreadability, drug content and in-vitro diffusion studies. The percentage of drug release from the niosomal gel was found to be 89.51%. The present study demonstrates prolongation of drug release, an increase the amount of drug retention into skin and improved permeation across the skin after encapsulation of Gentamicin Sulfate into topical gel.