In the recent years there's new development in field of colon specific drug delivery system. Colon targeted drug delivery system delivered as both local and systemic delivery of drugs. Local delivery might, for example, allow topical treatment of inflammatory bowel disease (IBD). Treatment might be increased once drug delivered to the target web site on the colon. Systemic side effects could also be reduced. Colon specific systems is most significant delivery of these drug that square measure unremarkably inactivated within the higher elements of the canal (GIT). Colonic drug delivery has gained augmented importance not only for the delivery of the medicine for the treatment of native illness related to the colon like Crohn’s disease, colitis, etc. but conjointly for the general delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive drugs and anti-diabetic agents. New systems and technologies are developed for colon targeting and to beat permeable method’s limitations. Colon targeting holds an excellent potential and still want a lot of innovative work. This review article discusses introduction of colon, need and approaches of colonic drug delivery, factor effecting colonic transition, colonic diseases and the novel and emerging technologies for colon targeting.

The aim and objective of the present work is to develop new simple, sensitive and validated UV spectrophotometric method for the estimation of Fexofenadine Hydrochloride in marketed formulation. The developments of analytical methods for the determination of drugs in bulk, in dosage forms or in body fluids have received a considerable attention in recent years because of their importance in quality control, bioavailability and pharmacokinetic study etc. Validation of developed Analytical methods according to ICH guidelines.

The present study was made to formulate and evaluate the effervescent tablet of Albendazole using wet granulation method to overcome the problems occurred in other marketed formulation of Albendazole and to determine the percentage release profile of drug. In this present study formulation were prepared from Albendazole as an active ingredient with effervescent bases in different concentrations and the flow characteristics are increased by adding microcrystalline cellulose as a bulking agent. The effervescent tablet is prepared by wet granulation method. In present work Preformulation studies were performed and prepared effervescent tablet of Albendazole were evaluated for hardness, friability, weight variation, disintegration time, FTIR. The formulation obtained from wet granulation method having improved flowability and dissolution rate. The dissolution studies were performed for three doses and the percentage release profile of three dose concentration F1, F2, F3 were found to be 99.7%, 89.75%, 83.25% respectively. In this, F1 dose give better release at the end of 15 mins. The percentage release profile of chewable tablet was found to be 99.87%, at the end of 30mins. So that effervescent tablet of albendazole was formulated and has improved percentage release profile within 15 mins.

Nanotechnology is a new field of science allowing fascinating research in many fields and its inventions could open up various milestones in the field of agriculture. Nano-fertilizers are being used extensively as a better option in comparison to bulk fertilizers. These help in the slow release of nutrients so that loss of nutrients can be minimized drastically and nutrients can be used judicially. Nanotechnology refers to the branch of science regarding the study of particles whose size ranges in nanometers, hence known as nanoparticles. Various physical chemical and biological methods can be used to synthesize nanoparticles. Nowadays “green synthesis “of nanoparticles is under practice so that nanoparticles can be synthesized in an environment-friendly manner. X-ray diffraction, NMR and various electron microscopy techniques can be used to synthesize nanoparticles. Here, we have discussed the significance of copper, iron, manganese and magnesium nanoparticles and their various roles in agricultural processes.

Topical microemulsion is principally supposed to be applied over the skin to produce target drug delivery. Microemulsions unit of measurement wonderful candidates as potential drug delivery system due to their improved drug solubilisation, long amount of your time and simple preparation and administration. Microemulsions have emerged as novel vehicles for drug delivery which permit sustained or controlled unleash for tissue, topical, stratum, ocular and channel administration of medicaments. Topical microemulsion supply the advantage of spontaneous formation, simple producing, natural philosophy stability, improved drug solubilisation of hydrophobic medication and increase bioavailability.