Lovastatin, is a potent competitive inhibitor of 3-hydroxy-3-methyl glutaryl coenzyme A. It is a powerful serum cholesterol-lowering drug in humans and other species. The major problem with this drug is its very low solubility in biological fluids which results in poor solubility after oral administration. Therefore Lovastatin with Poly ethylene glycol-6000 and PVP K30 in different weight ratios (1:1, 1:2, 1:3) were prepared to increase its water solubility. The solid dispersions were evaluated by solubility study, drug content, in-vitro drug release study, dissolution efficiency and characterized by FT-IR, Differential scanning calorimeter, X-ray diffraction and surface morphology by Scanning electron microscopy. It was prepared by Solvent evaparation methods by addition of superdisintigrant like Sodium starch glycolate, Crosscarmalose sodium, and Crospovidone in different concentration (1-5% w/w) and by effervescence technology by using combination of (2:3 ratio) Citric acid and sodium bicarbonate in different concentration (1-5% w/w) to enhance the patient compliance.

Applying plant communities diversity techniques and SPSS statistic analysis, we quantify how that the relationship between 18 (Sophora japonica) tree individual species’s crown volume and elevation along different elevation gradient in Ye County in the paper. We concluded that there is a significantly positive correlation between 18 (Sophora japonica) tree individual species’s crown volume and elevation (P<0.01). Elevation is the dominant environment driver of (Sophora japonica) tree individual species’s crown volume increased along elevation from 50m to 200m in Ye County in 2018. Therefore, understanding dynamic connecting of 18 (Sophora japonica) tree individual species’s crown volume and elevation can be not just applied to preserve of (Sophora japonica) species, but also applied to sustainable of biodiversity and processes of tree species’s crown volume along elevation gradient.

Out of all the dosage forms designed for the enhancement of medication, the orally disintegrating systems have been the favorite of product development scientists. Orally disintegrating tablets of ondansetron hydrochloride were developed by direct compression method using varying concentrations of different disintegrants like SSG and SCMC. Various physico-chemical properties and in-vitro dissolution characteristics of the formulations were analysed. Formulation F4 was found to have acceptable physic-chemical properties and the drug release was more than 80% within 10min. Which shows that the oral disintegrating tablets can be well utilized for emesis and other disease conditions also wherein the therapy requires patient compliance and in conditions which requires immediate release of the drug.

Single crystals have been grown from an aqueous solution of potassium hydrogen phthalate enriched with equimolar concentration acetamide at room temperature. The powder XRD analysis reveals that the chelate crystals belongs to triclinic system with cell parameter 𝑎=7.81Å, b=11.71Å, 𝑐 =6.32Å, 𝛼=93.78°, 𝛽=102.76°, 𝛾=94.86°. The coexistence of ghelate formation between KP and acetamide in the crystal confirmed by identifying the functional groups from FTIR spectrum. The grown crystal has UV absorption at 272 nm which indicate that the it is a potential candidate for NLO applications.

Oral solid dosage forms is the most widely use dosage forms for their easy mode of administration and many other advantages when compared to other conventional dosage forms. Under oral dosage forms, lozenges play a vital role in delivery of drugs to the patients. Lozenges are flavoured solid dosage form with one or more medicament, in a sweetened base and are intended to dissolve or disintegrate slowly in the mouth. They are medicated candies which are to be dissolved slowly in the mouth to sooth and lubricate the irritated tissues of throat. They are intended to produce local as well as systemic effect. Although they have many advantages, they have disadvantages too. Lozenges are of different types and are manufactured by different methods. Various types of synthetic as well as herbal lozenges are available in the market. The formulation and quality control tests of lozenges have been discussed in this review. Not only in children, in adults too, the acceptance ratio for lozenges as a dosage form is high.