Siddha medicine is one of the ancient medicines. Lore Shiva is the first saint to describe about the Siddha Medicine to Nandhi Devar and Nandhidevar passed on to other saints. The Tinea Infections are prevalent in tropical countries. Tinea infection is common between 5-16yrs of age. In India, the prevalence of Tinea infection is around 1 - 20yrs of age. Herbs are the safest forms of medicines for children. So the author has taken an herbal trial drug for the treatment of Padarthamarai (Tinea Infections) in Children for her present study to evaluate the therapeutic efficacy of the trial drug Kadalazhinjil Kudineer. Anti - fungal activity of the trial drug has been carried out by Disc Diffusion method against Trichophyton rubrum.
Forced degradation studies are useful in the development of analytical methodology, as it is of help to obtain a better understanding of active pharmaceutical ingredient (API) and drug product (DP) stability, and also to get insight into degradation pathways and degradation products. Heterocyclic chemistry is a crucial branch of organic chemistry as evident that two thirds of organic compounds are heterocyclic. Under forced degradation studies, the hetero atoms and the carbocyclic rings in the structure aundergo degradation to a different product than the primary drug structure. To study these products, various analytical methods are utilized. The current review discusses forced degradation studies and their impact on heterocyclic compounds.
Siddha formulations reduce the risk of side effects and some herbs rejuvenate the body by curing the ailments. In order to prove this scientifically, Qualitative and Quantitative analyses have to be carried out to prove the presence of active constituents. The main objective of this study is to find out the active constituents present in the trial Siddha formulation which helps in taking this medicine to next level in this scientific world. Physicochemical and chemical analyses were carried out. This study proves the presence of Iron, Starch and Reducing Sugar.
This study consisted of 250 patients including 176 (70.4%) males and 74 (29.6%) females with a mean age of 47.13 ± 24.31 years (range: 22-85 years). The renal stones were located at different sites. Pelvic stones accounted for 54.4% of cases, lower caliceal stones 7.6%, combined pelvic and one caliceal stone 35.6%; staghorn stones 22.4%; renal stones of the right kidney were found in 38.8% of cases, stones of the left kidney in 61.2%, and bilateral renal stones were found in 69 (27.6%) patients. Pre-operative hydronephrosis cases detected by Multi-Slice Computer Tomography (MSCT) were recorded as follows: Stone size: stone mean length: 2.41 ± 0.86 cm (1 – 4.8cm), stone mean width 1.62 ± 0.56cm (1-3.2cm). Access to the middle calyx was performed in 82.4% of cases, to the lower calices 16.8% and to the upper calices 0.8%. Mean operative time was 69.53±27.18 min (35-120 min). Intra-operative complications included 9 cases (3.6%) of haemorrhage not requiring blood transfusion. Post-operative complications occurred in 5.2% of cases, including 1 case of haemorrhage that was managed by selected embolization, 8 cases of fever, 3 cases of septic shock that was stabilized after a period of intensive care. The mean length of hospital stay was 4.57 ± 2.64 days (2-8 days). Nephrostomy tube was removed 2 -5 days after the operation (mean: 2.87 ± 1.43 days). Early post-operative stone-free rate was 80.7%. Follow-up examination and Double J stent removal was performed on 249 post-operative patients 01 month after the surgery with a stone-free rate of 96.8%. Conclusion: Ultrasound-guided Mini-Percutaneous Nephrolithotipsy performed on patients under spinal anaesthesia and placed in lateral position is a method that is highly beneficial for the patients, produces high stone-free rates (SFR) and less complications, and is quite easily applicable. It is highly recommended that Mini-PCNL be used in the treatment of kidney stones.
Siddha medicine is one of the ancient system of Indian medicine. Herbal remedies are given first preference in our system. Functional dyspepsia is a major health problem in all over the world among childrens. The frequency of Functional dyspepsia reached a percentage of 70%. The most common complaint in children aged late childhood and adolescent. Doctors may prescribe antacid, H2 blockers, prokinetics which produce side effects like constipation, diarrhea, headace, dry mouth, runningnose, dryskin. So the anti-flatulent activity of kattu maantha kudineer was experimented in rats by chicken pea method. The study results concluded that the drug kattu maantha kudineer has got significant anti-flatulent activity.